santeScore: 89/100For Perplexity

Pharmacological Research with Interactions and Contraindications

Comprehensive drug research with scientific sources, drug interactions, side effects and recommendations.

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Conduct comprehensive and up-to-date pharmacological research on:

**Drug/Molecule:** {{medicament_ou_molecule}}
**Use context:** {{contexte_utilisation}}
**Target population:** {{population_cible}}

Provide a structured report including:

## 1. GENERAL INFORMATION
- International nonproprietary name (INN)
- Main brand names
- Therapeutic class
- Detailed mechanism of action
- Available pharmaceutical forms

## 2. INDICATIONS AND DOSAGE
- Approved indications (with regulatory references)
- Documented off-label uses
- Standard dosage for target population
- Adjustments based on renal/hepatic function

## 3. CONTRAINDICATIONS AND PRECAUTIONS
- Absolute contraindications
- Relative contraindications
- Specific precautions for {{population_cible}}
- At-risk populations

## 4. DRUG INTERACTIONS
- Major interactions (with severity level)
- Relevant moderate interactions
- Interactions with food/substances
- Monitoring recommendations

## 5. ADVERSE EFFECTS
- Common effects (>1/10)
- Important though rare effects
- Documented long-term effects
- Side effect management

## 6. EVIDENCE BASE
- Level of evidence for {{contexte_utilisation}}
- Key clinical studies (with references)
- Learned society recommendations
- Current guidelines

## 7. PRACTICAL CONSIDERATIONS
- Recommended therapeutic monitoring
- Typical treatment duration
- Efficacy criteria
- Therapeutic alternatives

Requirements:
- Cite recent sources (<3 years preferentially)
- Indicate levels of evidence
- Mention any controversies
- Provide complete bibliographic references

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